Personal Accolades
Following Program members were invited
as speakers to international meetings:
• Yulin Lam. “Sulphones
in Combinatorial Synthesis” at International Symposium
on Chemical Biology and Combinatorial Chemistry, December 2006,
Shandong University, Jinan, PR China.
• Yang Daiwen. “Structure
determination of large proteins with uniformly 13C, 15N-labeled
samples” at 6th Biennial Conference of the Australian and
New Zealand Society for Magnetic Resonance (ANZMAG), February
2006, Australia.
• Yang Daiwen. “Structure
determination of large proteins without deuteration” at
22nd International Conference on Magnetic Resonance in Biological
Systems, August 2006, Germany.
• Yao Shao Qin.
“Catalomics - Advanced chemical proteomic tools for high-throughput
studies of enzymes” at ICOB-5 & ISCNP-25 IUPAC International
Conference on Biodiversity and Natural Products, July 2006,
Kyoto, Japan.
• Yao Shao Qin.
“Catalomics - Advanced chemical proteomic tools for high-throughput
studies of MMPs” at Post-symposium of ICOB-5 & ISCNP-25,
July 2006, Sendai, Japan.
• Yao Shao Qin. “The “Catalomics” of Matrix
Metalloproteases” at the International Conference of 43rd
Japanese Peptide Symposium/4th Peptide Engineering Meeting,
Nov 2006, Yokohama, Japan.
• Yao Shao Qin gave
the Mr & Mrs Sun Chan Memorial Award Lectureship entitlted
“Catalomics - The Use of Chemical Biology Tools for High-throughput
Studies of Enzymes” at the 9th International Symposium
by Chinese Organic Chemists (ISCOC-9) & 6th International
Symposium by Chinese Inorganic Chemists (ISCIC-6), Dec 2006,
Singapore
• Koh Hwee Ling.
“ Analysis of botanical and herbal preparations for contaminants.”
at the Annual Meeting of the American Association of Pharmaceutical
Scientists, Symposium on the Analytical Solutions to Regulatory
Challenges in Nutraceuticals, November 2006, San Antonio, Texas,
USA.
• Dr Kim Chu Young
is the recipient of the Office of Life Sciences Young Investigator’s
Award for 2006.
• A/P Yao Shao Qin
won an internationally prestigious award - the Mr and Mrs Sun
Chan Memorial Award in Organic Chemistry, given to Chinese organic
chemists under the age of 40 during the International Symposia
for Chinese Organic Chemistry. The past awardees include Luping
Yu (U of Chicago), Dan Yang (U of Hong Kong) / Gregory Fu (MIT),
Michael K.Chan (Ohio State U), and Shengming Ma (Shanghai Institute
of Organic Chemistry).
Publications
A total of 80 publications
saw print in peer-reviewed journals / edited book chapters in
2006. Of these, 22 were published in journals classified as
Tier 1 by the Office of Research, NUS. Some noteworthy findings
are highlighted in the following paragraphs:
Yang et al reported a
novel strategy for structure determination of large proteins
without deuteration (Nat. Methods, 2006, 3, 931-937). His research
findings were also highlighted in the NUS Research Gallery:
“Crossing the 30kDa barrier in NMR).
(http://www.nus.edu.sg/corporate/research/gallery/research89.htm).
Yao et al demonstrated
the ease and convenience of employing click chemistry in constructing
focused chemical libraries for rapid in situ screening of metalloprotease
inhibitors (Organic Letters 2006, 8, 713).
Chen et al reviewed the
progress in drug target exploration, proposed rules to guide
the search for druggable proteins and applied a statistical
learning method for predicting druggable proteins from their
sequences (Pharmacology Reviews, 2006, 58, 259).
Lu and co-workers reported
the synthesis of the first opioid peptide-derived antagonists
that do not contain a phenolic hydroxyl group at the 1-position
residue (Journal of Medicinal Chemistry, 2006, 49, 5382) Their
cyclic peptide, Dcp-c[D-Cys-Gly-Phe(pNO(2))-D-Cys] NH2, represents
a novel, potent mu opioid antagonist.
Journals classified
as Tier 1 under NUS system
1. Gao, Y.; *Lam, Y.L.
“[3+2] Cycloaddition Reactions in the Solid-phase Synthesis
of 1,2,3-Triazoles”, Org Lett, 2006, 8, 3283-3285.
2. Lin, Z.; Xu, Y.; Yang,
S.; *Yang, D.W. ”Sequence-Specific Assignment of
Aromatic Resonances of Uniformly 13C, 15N-Labeled Proteins with
Use of 13C- and 15N-edited NOESY Spectra”, Angew. Chem. Int.
Ed. Engl., 2006, 45, 1960-1963.
3. Zhang, X.; Sui, X.;
*Yang, D.W. “Probe methyl dynamics from 13C autocorrelated
and cross-correlated relaxation”, J. Am. Chem. Soc., 2006,
128, 5073-5081
4. Brath, U.; Akke, M.;
*Yang, D.W.; Lewis E. Kay.; Mulder, F.A.A.” Functional Dynamics
of Human FKBP12 Revealed by Methyl 13C Rotating Frame Relaxation
Dispersion NMR Spectroscopy”, J. Am. Chem. Soc., 2006, 128,
5718-27.
5. Srinivasan, R.; Uttamchandani,
M.; *Yao, S.Q. “Rapid Assembly and in situ Screening of Bidentate
Inhibitors of Protein Tyrosine Phosphatases (PTPs)”, Org.
Lett., 2006, 8, 713-716.
6. Wang, J.; Uttamchandani,
M.; Sun, L.P.; *Yao, S.Q. “Activity-Based High-Throughput
Profiling of Metalloprotease Inhibitors Using Small Molecule Microarrays”,
Chem. Commun., 2006, 717-719.
7. Wang, J.; Uttamchandani,
M.; Li, J.; Hu, M.; *Yao, S.Q. “Rapid Assembly of Matrix
Metalloprotease Inhibitors Using Click Chemistry”, Org. Lett.,
2006, 8, 3821-3824.
8. Wang, J.; Uttamchandani,
M.; Li, J.; Hu, M.; *Yao, S.Q. “Click” Synthesis of
Small Molecule Probes for Activity-Based Fingerprinting of Matrix
Metalloproteases”, Chem. Commun., 2006, 36, 3783-3785.
9. Yang, X.X.; Hu, Z.P.;
Chan, S.Y.; Duan, W.; Ho, P.C.L.; Boelsterli, U.A.; Ng, K.Y .;Chan,
E.; Bian, J.S.; *Chen, Y.Z.; Huang, M.; Zhou, S.F. ”Pharmacokinetic
mechanisms for reduced toxicity of irinotecan by coadministered
thalidomide”, Curr Drug Metab, 2006, 7 (4): 431-454.
10. Zheng, C.J.; Han, L.Y.;
Yap, C.W.; Xie, B.; *Chen, Y.Z. “Progress and problems in
the exploration of therapeutic targets”, Drug Discov Today,
2006, 11 (9-10): 412-420.
11. Zheng, C.J.; Han, L.
Y.;Yap, C. W.; Ji, Z. L.; Cao, Z. W.; *Chen, Y. Z. “Therapeutic
targets: Progress of their exploration and investigation of their
characteristics”,
Pharmacol Rev, 2006, 58 (2): 259-279.
12. Sunita, S; Zhenxing,
H; Swaathi, J; Cygler, M; Matte, A.; *Sivaraman, J. “Domain
Organization and Crystal Structure of the Catalytic Domain of
E.coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA”,
(2006) J Mol Biol, 2006, 359(4): 998-1009.
13. Liu, Y.; Wu, J.L.;
Song, J.X.; *Sivaraman, J.; Hew, C.L. “Identification of
a novel nonstructural protein, VP9, from white spot syndrome virus:
Its structure reveals a ferredoxin fold with specific metal binding
sites”, J. Virol, 2006, 80 (21): 10419-10427.
14. Ye, W.; Leow, D.; Goh,
Serena. L. M.; Tan, C.-T.; Chian, C.-H.; *Tan, C.-H. ”Chiral
bicyclic guanidines: a concise and efficient aziridine-based synthesis”,
Tetrahedron Letters, 2006, 47, 1007-1010.
15. Shen, J.; Nguyen, T.
T.; Goh, Y.-P.; Ye, W.; Fu, X.; Xu, J.; *Tan, C.-H. “Chiral
Bicyclic Guanidine Catalyzed Enantioselective Reactions of Anthrones”,
J. Am. Chem. Soc. 2006, 128, 13692-13693.
16. Jiang, Z.; Zhang, Y.;
Ye, W.; *Tan, C.-H. “P-C Bond Formation via Direct and Three-Component
Conjugate Addition Catalyzed by 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
(TBD)”, Tetrahedron Letters, in press.
17. Zou, P.; Oh, S.S.Y.;
Hou, P.L.; Low, M.Y.; *Koh, H.L. “Simultaneous determination
of synthetic phosphodiesterase-5 inhibitors found in a dietary
supplement and pre-mixed bulk powders for dietary supplements
using high-performance liquid chromatography with diode array
detection and liquid chromatography-electrospray ionization tandem
mass spectrometry” J Chromatogr A, 2006, 1104 (1-2): 113-122.
18. *Lu, Y.X.; Lum, T.K.;
Augustine, Y.W.L.; Weltrowska, G.; Nguyen. T.M.D.; Lemieux, C.;
Chung, N.N.; Schiller, P.W. “Replacement of the N-terminal
tyrosine residue in opioid peptides with 3-(2,6-dimethyl-4-carbamoylphenyl)propanoic
acid (Dcp) results in novel opioid antagonists”, J Med. Chem.,
2006,49 (17): 5382-5385.
19. Jiang, Z.Q.; Liang,
Z.; Wu, X.Y.; *Lu, Y.X. “Asymmetric aldol reactions catalyzed
by tryptophan in water” Chem. Commun. (Camb), 2006, (26):
2801-2803.
20. Wu, X.; Khoo, S.B.;
Tiekink, E.R.T.; Kostetski, I.; Kocherginsky, N.; Tan, A.L.C.;
Wilairat, P.; *Go, M.L. “Antiplasmodial activity of ferrocenyl
chalcones: Investigations into the role of ferrocene”, Eur.
J Pharm. Sc., 2006, 27, 175-187.
21. Shao, K.; Hou, Q.S.;
Duan, W.; *Go, M.L.; Wong, K.P.; Li, Q.T. “Intracellular
drug delivery by sulfatide-mediated liposomes to gliomas”,
J Control Release, 2006, 115 (2): 150-157.
Other Publications in
2006
1. Soh, C.H.; Chui, W.K.;
Lam, Y.L. “Efficient Synthesis of 2,4-Disubsituted-5-Aminoimidazoles
Using Microwave Irradiation”, J Comb Chem, 2006, 8, 464-468.
2. Gao, Y.; Lam, Y.L. “[3+2]
Cycloaddition Reactions in the Solid-phase Synthesis of 1,2,3-Triazoles”,
Org Lett, 2006, 8, 3283-3285.
3. He, R.; Ching, S.M.;
Lam, Y.L. “Traceless Solid-Phase Synthesis of Substituted
Xanthines”, J Comb Chem, 2006, 8, 923-928.
4. Tan, T.M.C.; Yang, F.;
Fu, H.; Raghavendra, M.S.; Lam, Y.L. “Design, Synthesis and
Biological Evaluation of Novel Purine Analogs as Inhibitors of
Multidrug Resistance Protein 4 (MRP4/ABCC4)”, J Comb Chem
accepted.
5. Anton, D.; Anna, D.;
Chui, W.K. “Microwave-assisted synthesis of s-triazino[2,1-b][1,3]benzoxazoles,
s-triazino[2,1-b][1,3]benzothiazoles and s-triazino[1,2-a]benzimidazoles”,
Synthesis-Stugtgart, 2006 No.4: 597-602 (2006).
6. Anton, D.; Anna, D.;
Chui, W.K. “1,2,4-triazolo[1,5-a][1,3,5]triazines (5-azapurines):
Synthesis and biological activity”, Heterocycles, 68, No.8:
1723 – 1759 (2006).
7. Anton, D.; Anna, D.;
Chui, W.K. “Unexpected reaction of 2-hydrazinopyrimidine
with maleic anhydride: syntheses of (8-amino-9-oxo-9,10-dihydro-8H-imidaz[1,2-a]pyrimidin-10-yl)acetic
acid and its azomethine derivatives”, Heterocycles, 68, No.4:821-828
(2006).
8. Anton, D.; Chui, W.K.
“Syntheses of 2-amino-s-triazino[1,2-a]benzimidazoles as
potential antifolates from 2-guanidino- and 2-guanidino-5-methylbenzimidazoles”,J.
Heterocyclic Chem, 43, No.1: 95-100 (2006).
9. Huang W.; Lin, Z.; Li,
D.; Gong, Z.; Yang, D.W.;” Characterization and expression
of a cDNA encoding a tubuliform silk protein of the golden web
spider”, Nephila antipodiana”, Biochimie, 2006, 88,
849-58.
10. Lin,Z.; Huang, W.;
Yang, D.W.;” Resonance Assignments of a Repeated Domain of
the Egg Case Silk from Nephila Antipodiana”, J. Biomol. NMR,
36, Suppl. 5, 17.
11. Lin, Z.; Sriskanthadevan,
S.; Huang, H.; Siu, C.H.; Yang, D.W. ”Solution structures
of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent
cell-cell adhesion”, Nat. Struct. Mol. Biol., 2006,13, 1016-22.
12. Zhang, L.; Yang, D.W.
“SCAssign: a Sparky extension for the NMR resonance assignment
of aliphatic side-chains of uniformly 13C, 15N-labeled large proteins”,
Bioinformatics, 2006, 22, 2833-4.
13. Xu,Y.; Zheng, Y.;Fan,J.;
Yang, D.W.” A novel strategy for structure determination
of large proteins without deuteration”, Nat. Methods, 2006,
3, 931-937.
14. Hu, Y.; Uttamchandani,
M.; Yao, S.Q. ”Microarray: a versatile platform for high-throughput
functional proteomics”, Comb. Chem. High Throughput Screening,
2006, 9, 203-212.
15. Srinivasan, R.; Huang,
X.; Ng, S.L.; Yao, S.Q “Activity-Based Fingerprinting of
Proteases”, ChemBioChem, 2006, 7, 32-36.
16. Uttamchandani, M.;
Wang, J.; Yao, S.Q. “Protein and Small Molecule Microarrays:
Powerful Tools for High-Throughput Proteomics”, Mol. BioSyst.,
2006, 2, 58-68.
17. Panicker, R.C.; Chattopadhaya,
S.; Yao, S.Q. “Advanced analytical tools for high-throughput
enzyme analysis”, Anal. Chim. Acta., 2006, 556, 69-79.
18. Chattopadhaya, S.;
Yao, S.Q. “Enzyme Assays on Chips,” in Enzyme Assays:
High-throughput Screening, Genetic Selection and Fingerprinting
(J.L. Reymond, ed), Wiley, 2006, Chapter 12. (ISBN: 3-527-31095-9)
19. Chattopadhaya, S.;
Tan, L.P.; Yao, S.Q. “Strategies for the Site-Specific Biotinylation
of Proteins using in vitro, in vivo and cell-free systems - Towards
Functional Protein Microarrays”, Nature Protocols, 2006,
1, 2386-2398.
20. Sun, H.; Chattopadhaya,
S.; Wang, J.; Yao, S.Q. “Recent development in microarray-based
enzyme assays: from functional annotation to substrate/inhibitor
fingerprinting”, Anal. Bioanal. Chem., 2006, 386, 416-426.
21. Wang, J.; Uttamchandani,
M.; Sun, H.; Yao, S.Q. “Small molecule microarrays: Applications
using specially tagged chemical libraries”, QSAR Comb. Sci.,
2006, 25, 1009-1019.
22. Sun, H.; Panicker,
R.C.; Yao, S.Q. “Activity-based fingerprinting of proteases
using FRET peptides”, Biopolymers, 2006, in press.
23. Cai, C. Z.; Yuan, Q.
F.; Xiao, H. G.; Liu, X. H.; Han, L. Y.; Chen, Y. Z. “Prediction
of transmembrane proteins from their primary sequence by support
vector machine approach”, Lect. Notes Comput., 4115: 525-533
2006
24. Yap, C. W.; Xue, Y.;
Li, Z. R.; Chen, Y. Z. “Application of support vector machines
to in silico prediction of cytochrome P450 enzyme substrates and
inhibitors”, Curr. Top. Med. Chem., 6 (15): 1593-1607 2006.
25. Xue, Y.; Li, H.; Ung,
C. Y.; Yap, C. W.; Chen, Y. Z. “Classification of a diverse
set of Tetrahymena pyriformis toxicity chemical compounds from
molecular descriptors by statistical learning methods”,Chem.
Res. Toxicol.,19 (8):2006,21,1030-1039.
26. Han, L.Y.; Cui, J.;
Lin, H.H.; Ji, Z.L.; Cao, Z.W.; Li, Y.X .; Chen; Y.Z. ”Recent
progresses in the application of machine learning approach for
predicting protein functional class independent of sequence similarity”,
Proteomics, 6 (14): 2006,4023-4037.
27. Cui, J.; Han, L.Y.;
Lin, H.H.; Tang, Z.Q.;Jiang, L.; Cao, Z.W.; Chen, Y.Z.”MHC-BPS:
MHC-binder prediction server for identifying peptides of flexible
lengths from
sequence-derived physicochemical properties”, Immunogenetics,
2006, 58 (8): 607-613.
28. Ji, Z.L.; Wang, Y.;
Yu, L.; Han, L.Y.; Zheng, C.J.; Chen, Y.Z.” In silico search
of putative adverse drug reaction related proteins as a potential
tool for facilitating drug adverse effect prediction”, Toxicol
Lett, 2006,164 (2): 104-112.
29. Ji, Z.L.; Li, Z.R.;
Wang, J.F.; Cai, C.Z.; Han, L.Y.; Zheng, C.J.; Chen, Y.Z.”Increasing
the odds of drug hit identification by screening against receptor
homologs”, Lett. Drug Des Discov., 2006, 3 (3): 200-204.
30. Bin, Yang, E.; Wei,
L.; Zhang, K.; Chen, Y.Z.; Chen, W.N. ”Tannic acid, a potent
inhibitor of epidermal growth factor receptor tyrosine kinase”,
J Biochem, 2006 139 (3): 495-502.
31. Xiao, H.G.; Cai, C.Z.;
Chen, Y.Z., ”Military vehicle classification via acoustic
and seismic signals using statistical learning methods”,
Int J Mod Phys C, 2006, 17 (2): 197-212.
32. Radjiman, S.; Han,
L.Y.; Wang. J.S.;Chen, Y.Z. “Super paramagnetic clustering
of DNA sequences”, J Biol Phys, 2006, 32 (1): 11-25.
33. Yap, C.W.; Xue, Y.;
Li, H.; Li, Z.R.; Ung, C.Y.; Han, L.Y.; Zheng, C.J.; Cao, Z.W.;
Chen,Y.Z. “Prediction of compounds with specific pharmacodynamic,
pharmacokinetic or toxicological property by statistical learning
methods”, Mini Rev Med Chem, 2006, 6 (4): 449-459.
34. Lin, H.H.; Han, L.Y.;
Zhang, H.L.; Zheng, C.J.; Xie, B.; Chen, Y.Z. “Prediction
of the functional class of lipid binding proteins from sequence-derived
properties irrespective of sequence similarity” J Lipid Res,
2006, 47 (4): 824-831.
35. Ji, Z.L.; Zhou, H.;
Wang, J.F.; Han, L.Y.; Zheng, C.J.; Chen, Y.Z. ” Traditional
Chinese medicine information database”, J Ethnopharmacol,
2006, 103 (3): 501-501.
36. Han, L.Y.; Lin, H.H.;
Li, Z.R.; Zheng, C.J.; Cao, Z.W.; Xie, B.; Chen, Y.Z.”PEARLS:
Program for energetic analysis of receptor-ligand system”,
J Chem Inf Model, 2006 46 (1): 445-450.
37. Lin, H.H.; Han, L.Y.;
Cai, C.Z.; Ji, Z.L.; Chen, Y.Z. ”Prediction of transporter
family from protein sequence by support vector machine approach”,
Proteins, 2006, 62 (1): 218-231.
38. Liu, Y.; Sivaraman,
J.; Hew, C.L. “Expression, purification and crystallization
of a novel nonstructural protein VP9 from white spot syndrome
virus” ACTA Crystallogr, 2006, 62: 802-804.
39. Xu, J.; Guan, Y.; Yang,
S.; Ng, Y.; Peh, G.; Tan, C.-H. “Chiral Imidazoline Promoted
Asymmetric Baylis-Hillman Reaction”, Chem. Asian. J. 2006,
1, 724 – 729.
40. Hou P.; Zou, P.; Low,
MY.; Chan, E.; Koh, H.L. “Structural identification of a
new acetildenafil analogue from pre-mixed bulk powder intended
as a dietary supplement”, Food Addit Contam. 2006, 23(9):870-5.
41. Hu, Z.P.;Yang, X.X.;
Chan, S.Y.; Xu, A.L.; Duan, W.; Zhu, Y.Z.; Sheu, F.S.; Boelsterli,
U.A.; Chan, E.; Zhang, Q.; Wang, J.C.; Ee, P.L.R.; Koh, H.L.;
Huang, M. Zhou, S.F. ”St. John's wort attenuates irinotecan-induced
diarrhea via down-regulation of intestinal pro-inflammatory cytokines
and inhibition of intestinal epithelial apoptosis” Toxicol.
Appl. Pharm., 2006, 216 (2): 225-237.
42. Oh, S.S.Y.; Zou, P.;
Low, M.Y.; Koh, H.L.”Detection of sildenafil analogues in
herbal products for erectile dysfunction”, J. Toxicol Env.
Heal. A. 2006, 69 (21):1951-1958.
43. Choong, A.M.F.; Teo,
S.L.M.; Leow, J.L.;Koh, H.L.; Ho, P.C.L.” A preliminary ecotoxicity
study of pharmaceuticals in the marine environment”, J. Toxicol.
Env. Heal., 2006, 69 (21): 1959-1970.
44. Chua, T.K.; Koh, H.L.
“Medicinal plants as potential sources of lead compounds
with anti-platelet and anti-coagulant activities” Mini-Rev.
Med. Chem., 2006 6 (6): 611-624.
45. Zou, P.; Hou, P.L.;
Low, M.Y.; Koh, H.L.;” Structural elucidation of a tadalafil
analogue found as an adulterant of a herbal product”, Food
Addit. Contam., 2006, 23 (5): 446-451.
46. Koh, H.L.; Wang, H.;
Zhou, S.; Chan, E; Woo, S.O. “Detection of aristolochic acid
I, tetrandrine and fangchinoline in medicinal plants by high performance
liquid chromatography and liquid chromatography/mass spectrometry”,
J Pharmaceut Biomed, 2006, 40 (3): 653-661.
47. Zou, P.; Oh, S.S.Y.;
Hou, P.L.; Low, M.Y.; Koh, H.L. “Simultaneous determination
of synthetic phosphodiesterase-5 inhibitors found in a dietary
supplement and pre-mixed bulk powders for dietary supplements
using high-performance liquid chromatography with diode array
detection and liquid chromatography-electrospray ionization tandem
mass spectrometry” J Chromatogr A, 2006, 1104 (1-2): 113-122.
48. Lau, A.J., Koh, H.L.
“Chapter 6. Quality control of herbs: Principles and procedures,
using Panax as an example”, In: Annals of Traditional Chinese
Medicine Volume 2. Current review of Chinese Medicine: quality
control of herbs and herbal material. eds. Leung PC; Harry Fong
and Charlie Xue, 2006, 87-115.
49. Koh, H.L. “Ginseng
– Man’s Panacea – and other Panax species”,
Innovation Magazine. The Magazine of Research and Technology:
Drugs from Plants, 2006, 6(2):12-14. Singapore: NUS and World
Scientific Publishing.
50. Min, C.; Min, X.; Lu,
Y.X.; Meng, Y.Z. ”Novel in situ preparation of crosslinked
ethylene-vinyl alcohol copolymer foams with propylene carbonate”,
Mater. Lett., 2006, 60 (27): 3286-3291
51. Cao, M.; Meng, Y.Z.;
Lu, Y.X. ”Synthesis of dimethyl carbonate (DMC) from CO2,
ethylene oxide and methanol using heterogeneous anion exchange
resins as catalysts”, React. Kinet. Catal. L, 2006, 88 (2):
251-259.
52. Wu, X.L.; Meng, Y.Z.;
Xiao, M.; Lu, Y.X. “Direct synthesis of dimethyl carbonate
(DMC) using Cu-Ni/VSO as catalyst”, J Mol Catal. A-Chem,
2006, 249 (1-2): 93-97.
53. Lu, Y.X. “Recent
advances in the stereocontrolled synthesis of antisense phosphorothioates”,
Mini Rev. Med. Chem., 2006, 6 (3): 319-330.
54. Zhou, T.Y.; Wang, Y.F.;
Li, X.M.; Zhang, Q.; Li, T.H. “Synthesis and characterization
of a fluorescein-labeled circular G-quadruplex” Bull Chem.
Soc. Jpn., 2006, 79 (8): 1300-1302.
55. Zhang, W.; Go, M.L.
“Quinone reductase induction activity of methoxylated analogues
of resveratrol”, Eur J Med Chem. Accepted for Publication
(2006).
56. Leow, J.L.; Baron,
R.; Casey, P.J.; Go, M.L. “QSAR of indoloacetamides as inhibitors
of human isoprenylcysteine carboxyl methyltransferase”, Bioorg
Med Chem Lett. Accepted for Publication (2006).
57. Liu, X.L.; Go, M.L. “Antiproliferative properties of
piperidinylchalcones”, Bioorg Med Chem, 2006, 14, 153-163.
58. Huang, E.; Ong, W.Y.;
Go, M.L.; Connor, J.R. “Upregulation of iron regulatory proteins
and divalent metal transporter-1 isoforms in the rat hippocampus
after kainate induced neuronal injury”, Exp. Brain. Res.,
2006, 170 (3): 376-386.
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